Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. the brand-name drug manufacturer of memantine, an Alzheimer’s disease treatment, introduced an extended-release version and tried to restrict patient access to the previous version. Tell your doctor if any of these symptoms are severe or do not go away: extreme … Find based on similar names, meanings, popularity, and more. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Memantine is a prescription drug that is also known by the brand name Namenda. This product is available in the following dosage forms: Portions of this document last updated: Feb. 01, 2020. Choosing a Name for Your Baby Learn about naming trends, get inspiration, and learn what parents wish they knew before naming their child. Memantine monotherapy is recommended as an option for managing Alzheimer's disease for people with: moderate Alzheimer's disease who are intolerant of or have a contraindication to AChE inhibitors, or; severe Alzheimer's disease. Memantine comes in three forms: immediate-release tablet, oral … Memantine does not cure Alzheimer's disease, but it is used to decrease the symptoms. Memantine was first marketed for dementia in Germany in 1989 under the name Axura. Memantine Capsule, Sprinkle, Extended Release 24 Hr Dose Pack (Capsule, Sprinkle Ext Rel 24Hr Pack) COMMON BRAND(S): Namenda XR. Memantine will not cure Alzheimer's disease, and it will not stop the disease from getting worse. Pharmacology . Copyright © 2021 IBM Watson Health. Memantine may also interact with antipsychotics, levodopa and other dopaminergic drugs. This agent appears to be a mild to moderate NMDA receptor antagonism, binding more frequently to the NMDA receptor cation channels. Memantine, a partial antagonist of N-methyl-D-aspartate receptor (NMDAR), approved for moderate to severe Alzheimer's disease (AD) treatment within the U.S. and Europe under brand name Namenda (Forest), Axura and Akatinol (Merz), and Ebixa and Abixa (Lundbeck), may have potential in alleviating additional neurological conditions, such as vascular dementia (VD) and Parkinson's disease (PD). Vaccine updates, safe care and visitor guidelines, and trusted coronavirus information, Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic School of Continuous Professional Development, Mayo Clinic School of Graduate Medical Education, FREE book offer – Mayo Clinic Health Letter. Patients on memantine (10 mg BID or 28 mg extended-release qDay) and donepezil 10 mg/day can be switched to Namzaric 28 mg/10 mg PO, taken once a day in the evening; Initiate the day following the last dose of memantine and donepezil administered separately; Dosage Modifications Severe renal impairment Tricyclo[3.3.1.13,7]decan-1-amine, 3,5-dimetyl-Foreign Names. Memantine may be found in some form under the following brand names: Namenda; Namenda XR; Memantine Drug Class. This medication works by blocking the action of a certain natural substance in the brain (glutamate) that is believed to be linked to symptoms of Alzheimer's disease. Initially approved by the FDA in 2013, memantine is an N-methyl-D-aspartate (NMDA) receptor antagonist used in the management of Alzheimer's Disease (AD). What Is Memantine? Memantine has not been studied in pediatric patients under 6 years of age or over 12 years of age. Memantine is a medication used to treat moderate to severe dementia associated with Alzheimer’s disease. Brand Name: Composition. List of brand or trade names of the generic drug called Memantine. Memantine systemic is used in the … Medication Uses | How To Use | Side Effects | Precautions | Drug Interactions | Overdose | Notes | Missed Dose | Storage. Memantine is an inhibitor of a receptor in the brain called NMDA. Data sources include IBM Watson Micromedex (updated 7 Dec 2020), Cerner Multum™ (updated 4 Dec 2020), ASHP (updated 3 Dec 2020) and others. Our general interest e-newsletter keeps you up to date on a wide variety of health topics. Back to Top. However, the drug does not cure Alzheimer’s. GENERIC NAME(S): Memantine On this page about Memantine (Generic Health) you will find information relating to side effects, age restrictions, food interactions, whether the medicine is available at a government subsidised price on the pharmaceutical benefits scheme (PBS) as well as other useful information. Side effects, drug interactions, dosing, warnings, and pregnancy safety information should be reviewed prior to taking this drug. Memantine is known by the brand name Ebixa®. 10 MG: ATC Code. SIVEM PHARMACEUTICALS ULC: Drug Identification Number. Memantine prevents too much calcium from entering brain cells. Memantine is used to treat the symptoms of Alzheimer's disease (AD; a brain disease that slowly destroys the memory and the ability to think, learn, communicate and handle daily activities). N06DX: ATC Descriptor. In 2003, the FDA approved Memantine for the treatment of both severe and moderate Alzheimer’s disease. Memantine (OS: BAN) D 145 (IS) DMAA (IS) Memantine Hydrochloride (OS: USAN, BANM, JAN) Memantine Hydrochloride (PH: USP 41) Brand Names. Memantine (brand name Namenda) carries the same risks as most other psychotropics in that a physical dependence can develop during use. Brand name ACT MEMANTINE. Because of its very long biological half-life, memantine was previously thought not to be a drug of abuse, although a few cases of sporadic recreational use have been described. Packing. 10 MG: ATC Code. Namenda is a medication that is prescribed to Alzheimer's patients to decrease abnormal excitement in the brain. © 1998-2021 Mayo Foundation for Medical Education and Research (MFMER). Memantine is used to treat moderate to severe Alzheimer's disease. Therapeutic Class. Company Name. Medindia's drug directory has currently 3 Brands of Memantine listed. Memantine is in a class of medications called NMDA receptor antagonists. ANTI-DEMENTIA DRUGS: Status. Chemical Name. 02446049: Ingredients. Brand name MEMANTINE. We comply with the HONcode standard for trustworthy health information -, miscellaneous central nervous system agents, Search the entire Drugs.com site for memantine. Memantine Hcl:. Memantine. Memantine is not a cure for Alzheimer's disease but it can help people with the disease. It works by decreasing abnormal activity in the brain. Company. Memantine (also known by its brand name Axura in Germany and to be marketed under the brand name Nameda in the U.S.) is a new class of anti-Alzheimer’s drug that blocks the transmission of glutamate, a critical brain chemical involved in memory and learning. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Namenda; Namenda XR; Namenda XR Titration Pack; Descriptions. Memantine (Brand name: Namenda) is prescribed for the treatment of symptoms from Alzheimer’s disease, such as dementia. Memantine, a partial antagonist of N-methyl-D-aspartate receptor (NMDAR), approved for moderate to severe Alzheimer's disease (AD) treatment within the U.S. and Europe under brand name Namenda (Forest), Axura and Akatinol (Merz), and Ebixa and Abixa (Lundbeck), may have potential in alleviating additional neurological conditions, such as vascular dementia (VD) and Parkinson's disease (PD). At this time, marketing authorization was expected late in the first half of 2002, and Lundbeck planned to launch memantine under the brand name Ebixa during the second half of 2002. Drug name Classification Mechanism of Action Indication Contraindication Adverse Reaction Nursing Responsibilities Generic Name Memantine Brand Name Namenda, Namenda XR Actual dosage, route, frequency 5 5 mg PO once NAMENDA belongs to a class of medicines called NMDA (N-methyl-Daspartate) inhibitors. However, the drug does not cure Alzheimer’s. Information on MEMANTINE for Service Users and their Families This leaflet provides general information about your medication. MEMANTINE is used to treat dementia caused by Alzheimer's disease. Namzaric; Descriptions. Memantine is not a cure for Alzheimer's disease but it can help people with the disease. Memantine is an inhibitor of a receptor in the brain called NMDA. [34] In the US, some CNS activities were discovered at Children's Hospital of Boston in 1990, and Children's licensed patents covering uses of memantine outside the field of ophthalmology to Neurobiological Technologies (NTI) in 1995. The generic Memantine is manufactured by one company. Memantine belongs to the group of medications known as NMDA receptor antagonists. ANTI-DEMENTIA DRUGS: Status. What day of the week was I born? Chemical formula: C12H21NDrugbank ID: DB01043ATC code(s): N06DX01, N06DA53, N06DA52. However, memantine will not cure AD or prevent the loss of these abiliti… Although memantine may have an advantage over placebo, it is important to remember that, on average, all the patients in the clinical trial got worse. Company Name. To refine your search select one of the options below. Although memantine may have an advantage over placebo, it is important to remember that, on average, all the patients in the clinical trial got worse. Memantine treatment was initiated at 3 mg/day and the dose was escalated to the target dose (weight-based) by week 6. Stopping Namenda abruptly can result in a withdrawal syndrome. Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below. 10 MG: ATC Code. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. The lowest price for Memantine (namenda) 20 mg is $0.93 per tablet for 84 tablets at PharmacyChecker-accredited online pharmacies.. Memantine (Brand name: Namenda) is prescribed for the treatment of symptoms from Alzheimer’s disease, such as dementia. Information on MEMANTINE for Service Users and their Families This leaflet provides general information about your medication. Memantine may improve the ability to think and remember or may slow the loss of these abilities in people who have AD. Brand name Packaging Size Status Date Created Date Updated Reports MEMANTINE: 30 Resolved 2018-04-16: 2018-06-30: 45930: MEMANTINE… Memantinum (Latin) Memantin (German) Mémantine (French) Memantina (Spanish) Generic Names. Drug name Classification Mechanism of Action Indication Contraindication Adverse Reaction Nursing Responsibilities Generic Name Memantine Brand Name Namenda, Namenda XR Actual dosage, route, frequency 5 5 mg PO once NAMENDA belongs to a class of medicines called NMDA (N- methyl- Daspartate) inhibitors. GENERIC NAME(S): Memantine On this page about Memantine (Generic Health) you will find information relating to side effects, age restrictions, food interactions, whether the medicine is available at a government subsidised price on the pharmaceutical benefits scheme (PBS) as well as other useful information. It works in the brain to block the effect of some chemicals that cause symptoms of Alzheimer's disease such as decreased memory and other mental functions. memantine systemic. Single Ingredient MEMANTINE HYDROCHLORIDE: Ingredient Strength. Important: The information below refers to products available in the United States that contain memantine. 02324067: Ingredients. Memantine is used to treat moderate to severe Alzheimer's disease. Memantine is available under the following different brand names: Namenda XR, and Namenda. Thought to act as a low- to moderate-affinity NMDA receptor antagonist, binding to NMDA receptor-operated channels. One preclinical study on monkeys showed that memantine was capable of inducing a PCP-like intoxication. Memantine is used to treat the symptoms of Alzheimer's disease (AD; a brain disease that slowly destroys the memory and the ability to think, learn, communicate and handle daily activities). Memantine is commonly sold under the trade name Namenda. Memantine is known by the brand name Ebixa®. N06DX: ATC Descriptor. Ebixa (CA) (UK), Namenda Pharmacologic class: N-methyl-D-aspartate receptor antagonist (NMDA) Therapeutic class: Anti-Alzheimer's agent Pregnancy risk category B Action Unclear. ANTI-DEMENTIA DRUGS: Status. It is used alone or with other medications totreat people with moderate-to-severe Alzheimer's disease.Memantine does not cure Alzheimer's disease, but it is used to decrease the symptoms. This medicine is available only with your doctor's prescription. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. All rights reserved. Drug information provided by: IBM Micromedex. Memantine comes as an immediate release tablet and liquid and as an extended release capsule form. Namenda. Before you buy memantine, compare prices at U.S., Canadian, and international online pharmacies. It comes in three forms: instant release tablet, oral solution, and extended release capsules. Mayo Clinic does not endorse companies or products. Memantine. The end result: generic memantine is now in pharmacies for as little as half the cost of brand-name Namenda. Brand name : NAMENDA US FDA Approval :October 2003 NMDA (N-methyl-D-aspartate) receptor antagonist Indicated for the treatment of moderate to severe Alzheimer… Slideshare uses cookies to improve functionality and performance, and to provide you with relevant advertising. There is no cure for Alzheimer's disease. Memantine is indicated for the treatment of all froms of dementia of the Alzheimer's type. Manufacturer patient information leaflets are also provided with all medicines. What is the most important information I should know about memantine (Namenda, Namenda XR)? Brand name Packaging Size Status Date Created Date Updated Reports ACT MEMANTINE: 30UD & 100's Resolved 2020-07-23: 2020-09-03: 120917: ACT MEMANTINE: 100 Actual shortage 2020-09-11: 2020-10-01: 124098: ACT MEMANTINE: 30UD Actual shortage 2020-10-15 It works in the brain to block the effect of some chemicals that cause symptoms of Alzheimer's disease such as decreased memory and other mental functions. Memantine and donepezil will not cure Alzheimer's disease, however, it may improve thinking ability, behavior, or functional ability. Drug class (es): miscellaneous central nervous system agents. MARKETED Shortage reports. Proposed Mechanism(s) of Action. If you require further information, speak to your doctor, pharmacist or nurse. Brand name MEMANTINE. Originally developed in the 1960s to treat diabetes, memantine was approved by the FDA in the US in 2003 for the treatment of moderate-to-severe Alzheimer’s disease . Stabilized on both donepezil and memantine. Memantine is part of the drug class: Other anti dementia drugs; Side Effects of Memantine. On this page about Memantine (Apo) you will find information relating to side effects, age restrictions, food interactions, whether the medicine is available at a government subsidised price on the pharmaceutical benefits scheme (PBS) as well as other useful information. Other memantine products are also available. US Brand Name. SIVEM PHARMACEUTICALS ULC: Drug Identification Number. Memantine brands in Pakistan Memantine is available in following trade names in Pakistan, click on any dosage to view brands of this drug. This content does not have an Arabic version. Brand name : NAMENDA US FDA Approval :October 2003 NMDA (N-methyl-D-aspartate) receptor antagonist Indicated for the treatment of moderate to severe Alzheimer… LinkedIn emplea cookies para mejorar la funcionalidad y el rendimiento de nuestro sitio web, así como para ofrecer publicidad relevante. Generic drugs usually have lower cost than the brand name … Oral doses of memantine 3, 6, 9, or 15 mg extended-release capsules were administered once daily to patients with weights < 20 kg, 20-39 kg, 40-59 kg and ≥ 60 kg, respectively. Memantine may also be indicated in other types of dementia. What important events happened … Brand names; Why is this medication prescribed? Memantine and the brand name Namenda are available in the U.S. and at verified international online pharmacies. USES: Memantine is used to treat moderate to severe confusion related to Alzheimer's disease.It does not cure Alzheimer's disease, but it may improve memory, awareness, and the ability to perform daily functions. Drug Name : Memantine. Other memantine MRP Rs. Advertising revenue supports our not-for-profit mission. Memantine Brand Names. It was first developed in the 1960s for the treatment of diabetes. Memantine is a primary aliphatic amine that is the 3,5-dimethyl derivative of 1-aminoadamantane.A low to moderate affinity uncompetitive (open-channel); NMDA receptor antagonist which binds preferentially to the NMDA receptor-operated cation channels. By doing so this medication is helping them live with Alzheimer's disease by slowing the progression of the Disease. Description and Brand Names. 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